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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN14
All Species:
18.79
Human Site:
Y692
Identified Species:
41.33
UniProt:
Q15678
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15678
NP_005392.2
1187
135261
Y692
E
V
P
Q
L
P
Q
Y
H
H
K
K
T
F
S
Chimpanzee
Pan troglodytes
XP_001171329
1187
135241
Y692
E
V
P
Q
L
P
Q
Y
H
H
K
K
T
F
S
Rhesus Macaque
Macaca mulatta
XP_001106167
1187
135194
Y692
E
V
P
Q
L
P
Q
Y
H
H
K
K
T
F
S
Dog
Lupus familis
XP_849236
1187
134903
Y692
E
A
H
Q
L
P
H
Y
H
H
K
K
T
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62130
1189
135012
L692
G
G
H
E
V
H
G
L
P
Q
Y
H
H
K
K
Rat
Rattus norvegicus
Q62728
1175
133393
K698
G
S
G
G
Y
S
H
K
K
S
L
S
D
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511302
1193
135259
T697
E
V
Q
Q
Q
L
P
T
Y
L
H
K
K
T
F
Chicken
Gallus gallus
XP_419419
1191
135566
Y697
E
V
Q
Q
V
P
H
Y
H
H
K
K
T
F
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339962
834
94004
S387
E
E
E
F
E
D
D
S
G
R
H
T
P
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
V579
T
S
S
P
R
N
S
V
A
S
Y
S
S
F
A
Sea Urchin
Strong. purpuratus
XP_796215
1318
147575
Q703
M
Y
S
R
H
V
S
Q
G
Y
Q
Q
Q
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
95.6
N.A.
91.5
53.7
N.A.
87.9
84.9
N.A.
32.8
N.A.
N.A.
N.A.
24.7
34.5
Protein Similarity:
100
99.7
99.5
97.2
N.A.
95.6
70.7
N.A.
92.1
91.5
N.A.
48.1
N.A.
N.A.
N.A.
42
51.7
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
26.6
80
N.A.
13.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
80
N.A.
13.3
6.6
N.A.
33.3
86.6
N.A.
13.3
N.A.
N.A.
N.A.
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% D
% Glu:
64
10
10
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
55
10
% F
% Gly:
19
10
10
10
0
0
10
0
19
0
0
0
0
0
0
% G
% His:
0
0
19
0
10
10
28
0
46
46
19
10
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
10
0
46
55
10
10
10
% K
% Leu:
0
0
0
0
37
10
0
10
0
10
10
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
28
10
0
46
10
0
10
0
0
0
10
0
0
% P
% Gln:
0
0
19
55
10
0
28
10
0
10
10
10
10
10
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
19
19
0
0
10
19
10
0
19
0
19
10
0
64
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
0
10
46
10
10
% T
% Val:
0
46
0
0
19
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
46
10
10
19
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _